Kathryn A. Cunningham is the Director of the UTMB Health Center for Addiction Sciences and Therapeutics at The University of Texas Medical Branch. Substance use disorders (SUDs) pose a significant challenge, as they often damage brain function related to motivation and decision-making. While psychedelics like psilocybin have shown promise in helping with recovery, their risks—such as hallucinations and safety concerns—make them challenging to use widely. Dr. Cunningham is working on a solution that focuses on developing new compounds that similarly boost brain function but without harmful side effects. This approach could open up new, safer treatment options for those struggling with cocaine and stimulant addiction, areas where no approved medications currently exist.